Hello everyone, I have a problem, I always play in windowed mode, but when I move the crosshair down, it activates the NexusDock in overlay

Is it possible to activate the Nexusdock overlay by one key? I don't want to activate it when I drag the mouse to the edge

That is by design - if you are playing in window mode, then the game is treated just like any other window. If you don't want the dock to activate, play in full screen mode.

Anyway, try undocking the dock and leave it floating. If auto-hide is enabled, instead of hiding into the screen edge, it will now collapse into a control icon, and it will no longer respond to screen edge bumps. Or use edge swipe instead of edge bump as the activation method.